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Monday, 13 June 2011

New mutations from dad or mum? Speed of human mutation revealed in new family genetic research



60 new mutations in each of us: Speed of human mutation revealed in new family genetic research

Each one of us receives approximately 60 new mutations in our genome from our parents. This striking value is reported in the first-ever direct measure of new mutations coming from mother and father in whole human genomes published today.




For the first time, researchers have been able to answer the questions: how many new mutations does a child have and did most of them come from mum or dad? The researchers measured directly the numbers of mutations in two families, using whole genome sequences from the 1000 Genomes Project. The results also reveal that human genomes, like all genomes, are changed by the forces of mutation: our DNA is altered by differences in its code from that of our parents. Mutations that occur in sperm or egg cells will be 'new' mutations not seen in our parents.

Although most of our variety comes from reshuffling of genes from our parents, new mutations are the ultimate source from which new variation is drawn. Finding new mutations is extremely technically challenging as, on average, only 1 in every 100 million letters of DNA is altered each generation.

Previous measures of the mutation rate in humans has either averaged across both sexes or measured over several generations. There has been no measure of the new mutations passed from a specific parent to a child among multiple individuals or families.

"We human geneticists have theorised that mutation rates might be different between the sexes or between people," explains Dr Matt Hurles, Senior Group Leader at the Wellcome Trust Sanger Institute, who co-led the study with scientists at Montreal and Boston, "We know now that, in some families, most mutations might arise from the mother, in others most will arise from the father. This is a surprise: many people expected that in all families most mutations would come from the father, due to the additional number of times that the genome needs to be copied to make a sperm, as opposed to an egg."



Professor Philip Awadalla,who also co-led the project and is at University of Montreal explained: "Today, we have been able to test previous theories through new developments in experimental technologies and our analytical algorithms. This has allowed us to find these new mutations, which are like very small needles in a very large haystack."

The unexpected findings came from a careful study of two families consisting of both parents and one child. The researchers looked for new mutations present in the DNA from the children that were absent from their parents' genomes. They looked at almost 6000 possible mutations in the genome sequences.
They sorted the mutations into those that occurred during the production of sperm or eggs of the parents and those that may have occurred during the life of the child: it is the mutation rate in sperm or eggs that is important in evolution. Remarkably, in one family 92 per cent of the mutations derived from the father, whereas in the other family only 36 per cent were from the father.

This fascinating result had not been anticipated, and it raises as many questions as it answers. In each case, the team looked at a single child and so cannot tell from this first study whether the variation in numbers of new mutations is the result of differences in mutation processes between parents, or differences between individual sperm and eggs within a parent.

Using the new techniques and algorithms, the team can look at more families to answer these new riddles, and address such issues as the impact of parental age and different environment exposures on rates of new mutations, which might concern any would-be parent.

Equally remarkably, the number of mutations passed on from a parent to a child varied between parents by as much as tenfold. A person with a high natural mutation rate might be at greater risk of misdiagnosis of a genetic disease because the samples used for diagnosis might contain mutations that are not present in other cells in their body: most of their cells would be unaffected.

More information: Conrad DF et al. (2011) Variation in genome-wide mutation rates within and between human families. Nature Genetics, published online 12 June 2011. doi:1038/ng.856

Provided by Wellcome Trust Sanger Institute (news : web)

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Malaysian taking office in London instead of Kuala Lumpur





Malaysian set to take up duties as RICS president in London

By LIZ LEE lizlee@thestar.com.my


PETALING JAYA: A Malaysian elected as the first non-British president of the Royal Institution of Chartered Surveyors (RICS) will conduct his duties from the heart of the British political powerhouse in London.

Ong See Lian, who will head the prestigious RICS for the 2011-2012 session, will move into an office in the centre of Parliament Square, overlooking the Big Ben and Westminster Abbey, on July 4.

The 60-year-old quantity surveyor from Petaling Jaya, who beat off opposition to win the post in March, will live in a flat at Vauxhall, South London, with his wife Cheah Yoke Ling.



“It is a modest office, more functional than lavish, but I think my window has the best view of London.

Sunday, 12 June 2011

Niceties of Obedient Wives Club (OWC), Obedient Servants of colonial masters, cont...




FB users urged to support anti-OWC drive

By ISABELLE LAI  isabellelai@thestar.com.my 

PETALING JAYA: “Please save my mummy.”

Facebook users can choose this slogan among five variants to voice their concern over a drive by the so-called Obedient Wives Club (OWC) to get women to be subservient to their husbands.

The man behind the anti-OWC campaign, Matthew Ong, said those who wanted to show their support needed to change their profile pictures to the wallpaper of the Facebook campaign, which featured five slogans, including “Please save my mummy”.

The other variants are “Please save my wife/daughter/girlfriend/yourself”.

Ong's attempt to debunk the OWC drive followed recent statements by leaders of the controversial club that social ills, such as prostitution, domestic abuse and human trafficking, were allegedly caused by wives who were not obedient to their husbands and had failed to sexually satisfy them.

The club gathered international headlines last week for its message that wives needed to obey and serve their husbands in every way, including being “better than a first-class prostitute” in bed.

Ong urged more Facebook users to join the group “We Do Not Want Sexist Nonsense From Global Ikhwan Sdn Bhd”, which currently has 3,824 members.


A happy man, a happy home

The Obedient Wives Club hopes that Malaysians can give them a chance to prove their noble aspirations.

THE first thing you see when you walk into the office of the now infamous Obedient Wives Club (OBW) in Rawang, Selangor, is a huge double bed covered with a velvety red bedspread.

In that situation, how does one keep “bordello”, “prostitutes” and “service” from popping to mind?
Noticing our discomfort, the club's national director Fauziah Ariffin gives a small laugh.

“The reporters who came this morning straight away asked us if this is for the sex lessons in our workshop!” shares the slight woman jovially before adding, on a more serious note, “That is how everything has been twisted out of proportion.”

She quickly tries to set things right.

“Sex workshops are not on the agenda for the club; it is haram!”

What they will have, she states, are motivational talks, counselling sessions and discussions among their 1,000 members.

“Of course, we welcome anyone to join,” she enthuses.

The newly-launched wives club catapulted to notoriety around the world recently when its vice-president Dr Rohaya Mohamed said the secret to a happy family and subsequently the solution to all of society's ills is a happy man at home, which can be achieved if women served their husbands like “first-class prostitutes”.

The outrage the remark has incurred is not surprising. Was the remark based on facts? Definitely, avows Fauziah.

“You just need to open the newspaper or watch the news on TV: there are so many sex-related social problems rape, incest, prostitution and sex trafficking.”

Men will not be committing these crimes if they are sexually satisfied at home, she stresses.

“The key to make a man gentle and loving is a first-class loving wife an obedient wife. When the wife is obedient, the husband will be happy and gentle. They will not look elsewhere for the loving they need.”
And like simple economics, cutting off the “demand” for the illegal “sex” will cut the supply.

“The authorities have come up with a lot of solutions and conducted various raids or operations to nip these social problems, but they still exist. The solution we are proposing is one that is guaranteed to work, as it is backed by the Quran,” she explains.

Committee member Siti Maznah Mohamed Taufik tries another argument to demonstrate how a sexually frustrated man can cause violence in society.

“Just yesterday, there was a story about a man who hit his wife with a lesung (pounding stone) because she refused to have lunch with him. Do you believe that? It does not make sense. Just because of lunch, a man would hit his wife until she is hospitalised? I'm sure it is because she did not give him any the night before. That's why he was furious with her.”

For “obedient” wives, Fauziah and Maznah are outspoken and frank about their belief. People have a misconception that they are meek women who are anti-career and anti-education, they say.

“We were all working professionals; I was an accountant and she was an engineer. We were both educated in Australia,” says Fauziah, pointing to Maznah.

“So we have been exposed and we know how difficult it is to balance work and marriage.”
Now, she says, they are businesswomen for Global Ikhwan Sdn Bhd, the corporation that runs the OWC, and travel around the world five to seven times a year.

How do they find time to practise what they preach then? “We become obedient wives when we meet our husband. You can say that absence makes the heart grow fonder,” Maznah quips.

She adds that they are constantly learning and reminding themselves about how to become obedient. Many working women, however, are content to neglect their wifely duties, she says.

“With housework, we can get help from maids, our children or family. But with sex, who can help? And if we go back to the time of Adam and Eve, that is the real responsibility of women (to fulfil the sexual needs of men) but many women are neglecting that responsibility, so men have to pay thousands of ringgit just to satisfy their sexual needs.”

And that is where the whole idea of the first-class prostitute service originated, explains Fauziah.

“That is what the statement means you need to be as skilful as a first-class prostitute and give more. It is not about the person, it is the service your appearance, the way you speak to your husband, the way you understand your husband. And it is not just in bed but in everything a wife has to be the best she can. ”
She laments the way her vice-president's words have been misconstrued.

“We are not equating a wife to a prostitute. A wife provides love and affection which a prostitute doesn't,” says Fauziah.

“We wanted to say that a good wife needs to be like a bidadari (an angel), but how many of us have met an angel? It will be difficult for people to relate to it.

“But mention prostitutes, and everyone will be able to visualise and understand the concept.”

Another question emerges: how do they know what first-class service from “elite” prostitutes is like?
“I know because I read about it in magazines and books. For example, I've read many thrillers of how KGB female spies are trained to use their sexuality to seduce men. We just want the service, not to be like the person. Those who read a lot will know what we mean,” shares Fauziah.

They may not look like your typical sex pots but the two women do come across as warm and affectionate.

Malaysians, especially Malaysian Muslims, are hypocritical when it comes to sex, laments Fauziah.

“They act all prudish and don't want to talk about sex. When they get older, the women start distancing themselves from their husband while many sleep in separate bedrooms when scientifically it has been proven that men have sexual needs until they die. That is why we have many cases of grandfathers raping their grandchildren.”

She, however, refutes the notion that the club is unfairly putting the blame on women.
“Men are responsible too. We have never denied that. But the root of the problem is that women are not fulfilling their responsibility to the men.

“If we go back to the Quran, you can see that God says women play a big role in shaping society but to do that they need to be good wives in the whole sense. Men and women are not created equal but women today do not understand that. Instead, they keep demanding that men understand them and fulfil all their wishes.”

The way she explains it, it is indeed a case of “men are from Mars and women are from Venus”.

“Men have only one desire, which is for women, while women have nine desires for a new handbag, new shoes and many more. That is how God created us, and there is a gap of understanding between the sexes.

“That is why women are required to be obedient, so that they can bridge the gap between them and their husband,” says Fauziah.

“Women today, however, feel that it is the men who should understand them and fulfil all their needs,” Maznah interjects.

They believe that is the main reason why society is in a mess (huru hara): because women are demanding for equality in work and marriage.

Fauziah is not worried about young girls getting the wrong message about sex.

“We have children too. If the girls are good and have enough religious education, they will not misunderstand our message and stray from the right path. The basis of our belief is to love and be fearful of God. No religion in the world asks their believers to disobey their husbands,” she says.

As for the effect all the sex talk is having on their image as Muslim women, both Maznah and Fauziah are not too concerned either.

As Maznah puts it, “In Islam, we believe that God created women for men. Sex is natural. If you look at the Quran, there are a lot of references to sex.

“God even promised sexual pleasure from beautiful bidadari in heaven for those who are good. So are you saying that God is sex-crazed or obscene?”

Is sex the only happy factor in marriage?

By HARIATI AZIZAN sunday@thestar.com.my

AFTER more than a decade of marriage, 40-something Susan* and her husband are still hot in between the sheets. However, all the action in bed is cooling off her feelings for her husband.

“I am tired all the time but he is just insatiable,” she confides.

Outside the bedroom, the two management-level professionals hardly communicate, unless there are problems with their children, or huge bills to settle.

Worse, she says, both are addicted to their smartphones. “When we are together, our attention is on our phone reading updates and e-mail or just trying out new Apps.”

Although divorce is not on their minds, Susan admits that the romance is missing from their relationship.

Paul Jambunathan, a consultant clinical psychologist at Sunway Medical Centre, says lack of communication between husband and wife is the main cause of extra-marital affairs and divorces.

“The problem starts when the husband and wife start living on different planets and stop sharing their emotions or stop talking about something other than their children, bills and other domestic problems,” says Jambunathan, who is also a senior lecturer at Monash University Malaysia.

In a relationship, there are many variables because it involves two personalities or personas, he says.

“The two personas interact verbally and non-verbally. One of the most important issues in interaction is intimacy. Unfortunately, we have been relating intimacy to sex and equating sex only to sexual intercourse.

What I am trying to say is that while sex is integral to a happy marriage, we need to define what sex is. Is it only intercourse?”

As he explains, sex is the sexuality expressed between two people and there is a wide spectrum of sexual behaviour.

“If you have feelings for someone, even touching and holding hands will already make you sexually excited. When you later get married and build on that love you have intercourse, sleep together, talk and spend more time together a different kind of sexual intimacy is built.”

Hence, Jambunathan, who has more than 25 years' experience as a consultant, is vexed by the comments made by the Obedient Wives Club (OWC), which suggested that to keep a man from straying from his marriage, the wife needs to please him in bed like a “first-class prostitute”.

“When couples in trouble seek my advice, they tell me that intercourse and sleeping in the same room do not necessarily help (mend their relationship). Sometimes it even creates complications.”

He stresses that it should not be about intercourse but making love.

“Love is not intercourse as people often equate it to; intercourse is a personal, committed and intricate intimacy but it does not last very long. Usually one hour after the act, the feeling is gone.”

Health research consultant Siti Norazah Zulkifli agrees, saying that sex will not sustain a marriage if there are other major problems.

“Sex, no matter how good, is not the only thing that keeps a marriage happy. Couples choose to marry for various reasons love, attraction (physical and mental), companionship, economics, social expectations, offspring ... Sex is only one reason.

“In tribal cultures, for example, land ownership or the number of cows he or she owns may be a factor. Actually, economics may well be a consideration in modern marriages too, and how important one factor is over another depends on the individual.”

Once married, and especially over time, she says, other factors will contribute towards maintaining happiness in marriage.

This includes whether they meet each other's expectations, how they cope with stressful events and their level of commitment to their marriage, compromises each has to make for the other, whether they “grow apart” as individuals and their marital values.

“Not everyone subscribes to monogamy, for example,” she says. Siti Norazah nonetheless concedes that in the literature on what makes happy marriages, sex does predominate as a topic of discussion.

“It may seem that most marriages break up because of some sexual issue (notably, sexually unsatisfied husbands). We should be aware, however, that sometimes what is expressed as a sexual problem has its roots in something else, such as failed expectations. For example, if a person feels resentment towards his or her spouse, it will affect his or her sexual desire to that spouse.”

Some people, perhaps men more so, associate sex with love, she points out.

“Some men feel that his wife doesn't love him if she rejects his sexual advances. Equally, a wife would feel the same way if her husband doesn't want to make love to her. In sum, an individual's sexual development is complex, beginning from a young age, and becomes intrinsic to his or her personality.”

Siti Norazah makes an interesting point, highlighting that most of the studies on marriage and sexual attitudes are based on Western ideals.

“We should recognise that people have different sexual attitudes and sex drives. How they were brought up, sexual norms in their society and culture, exposure to external social influences (for example living abroad or the media), their personality, their sex hormone levels (testosterone, notably) and other factors influence how important sex is to them and how they express their sexual needs.”

Still, she feels that in conservative and chauvinistic cultures, men may not want their wife to be sexually aggressive or “act like a prostitute”.

She opines that the OWC prostitute statement will create a gender bias one that will compound the attitude that there are two types of women the ones they will marry and the ones with whom they will have fun (have sex with) but never marry.

“Conversely, girls may be brought up to repress their sexual desire so the message that their husband's happiness depends on her sexual performance puts the blame on her should there be any marital problem.

“For a married couple, it is not sex per se but sexual incompatibility that could breed resentment or dissatisfaction and cause marital problems such as adultery and divorce.”

According to consultant psychologist Valerie Jaques, a study she conducted a number of years ago showed that one of the most significant factors for high marital satisfaction is when there is a greater awareness and accurate perception of the needs of a marriage partner.

“So when the husband is aware of the wife and perceives her needs accurately by effective communication and vice-versa then there is high marital satisfaction.”

She highlights that it is not just intercourse that reflects how good a marriage is, but rather the intimate and mutual sex in the relationship.

“Very often, if one party is upset or hurt with the other and there is a strain in the relationship, there is lack of sexual intimacy in the marriage. This is different from just having sex to fulfil a need,” she shares.

More importantly, stresses Jaques, although sex is one of the many important elements that make up a marriage, it definitely does not mean that marriage is a legal means for a man to rape his wife. Neither should the wife allow the husband to take advantage of her for his needs.

“Many women are made to believe that they do not have rights in their marriage and that only the husband's rights are to be met,” she says.

Jambunathan agrees that a man does not have the right to demand for sex without consideration of the woman's needs and wants.

“He cannot say I want it now, so give it to me. The woman is an equal partner in the relationship and she has a right to decide the level of intimacy and the platform of the relationship.”

He also disputes the belief that men's biological make-up makes them sexual at all ages and that they have high sexual needs until they die.

“As you get older, your body gets older and your biology will not allow you to have intercourse,” he says, highlighting that half of heart patients are men, and that “many cannot get it up because of their medication”.

However, attitude may come into play and corrupt emotions where the emotions are twisted “will make you think you must have intercourse at any age 60, 70, 80 regardless of your partner's wants”, he says.

* Not real name

Related Posts:

Wives Club (OWC) to offer sex lessons

Signing off for the niceties of colonial masters, obedient servants, wives ...

Innovation management





http://blogs-images.forbes.com/stevedenning/files/2011/06/light-bulb-on-greenboard.jpg

Steve Denning RETHINK

Because it is its purpose to create a customer, any business enterprise has two – and only these two – basic functions: marketing and innovation.

The June issue of Harvard Business Review is—happily—about one of a business’s two  basic functions: innovation. The cover title is “How Great Leaders Unleash Innovation”. The “Spotlight” inside includes four articles on product innovation:
  • How Procter & Gamble [PG] has gone from achieving 15% of the profit and revenue objectives in 2000 to 50% today by setting up an “innovation factory” (p. 64)
  • How the “ambidextrous CEO” at Misys (and elsewhere) manages the tension between innovation and core products (p.74)
  • How Scott Cook at Intuit [INTU] catalyzed his employees to innovate (p. 82).
  • How Rain Bird (among other firms) discovered hidden gold in its reject pile (p.88).
Three other articles also bear on the topic of innovation:
  • The birth of outsourcing back-office services in India at Genpact [G] (p. 45)
  • How customers can inspire employees (p. 96).
  • How firms can compete against free (p.104).

The alarming state of innovation in business today

The seven articles are presented as illustrations of management excellence and thus exceptions to what is happening in organizations more generally. As it happens, the articles collectively give us an illuminating picture of the normal state of innovation in business today—perhaps even more illuminating than the editors and authors intended.

Before we get to evaluate the recommendations contained in the seven articles (which I will do in later parts of this article), let’s first take stock of what the articles say about the general status of innovation today. In this way, we will be able to see whether the recommendations in the articles are responsive to the problems that business enterprises face today.

The picture is not pretty.

Innovation is consistently assigned low priority

Given that innovation is one of the two basic functions of an enterprise, it is strange to learn that in business today:

“competition for resources and attention usually gets resolved in favor of the established business.” (p.77) (emphasis added)

Innovation is viewed as “an irritating drain on resources.” 

Just think about that for a moment. Instead of innovation being one of only two main functions of an organization, in the world of business today innovation “usually” gets no look-in at all. Rather than being the main function of the firm, management is typically hostile to innovation.

For instance, at one company, when the CEO asked his senior executives to prepare a plan for coping with global economic crisis in 2008, their response was a proposal to cut a $3 million investment in disruptive innovation.

Remarkable! Is this unusual? No. As the authors say:
 “It’s a familiar story.” (p.75) 

In an example from another firm:

“A new innovation emerged: the portable handheld scanner. A small team, several layers down within the scanners unit developed a portable scanner. They believed the innovation would revolutionize the market, but they couldn’t get the attention from managers whose focus was winning market share for the flatbed [scanner].” Then a senior executive “intervened with $10 million of funding to validate the portables business, but within months, the scanners had diverted the funds to plug a hole in its budget. The portables R&D team was left with no funds and no authority.” (p. 78)

And why is that? We learn that

“executives almost always bow to the more pressing claims of the core business, especially when times are hard. Innovations … face an uphill battle to secure a share of the firm’s capital. They lack scale and resources and are usually underrepresented at the top table. At best, the leaders of the established business units ignore such projects. At worst, they seem them as threats to the firm’s core identity and values. Often innovation’s only friend is the CEO.” (emphasis added)

Extraordinary! This is after all 2011 that HBR is talking about, not 1911. This is the world of global competition and whitewater technological change, where innovation is crucial to the future. Future is apparently not management’s problem. It’s the lone CEO versus the entire management structure.

“At the best of times, innovation investments can be painful. Typically success rates are low and returns on investment far from assured. The returns that do materialize moreover rarely do so in the short term. That makes innovation hard to justify when cash is tight—even when everyone knows it’s essential to the long term success.” (p.89)

Where innovation teams do exist:

“most consisted of part-time members—employees who had other responsibilities pulling at them.” (p.71).

Even the CEO often ducks responsibility

And what is the role of our CEOs? We learn that

often … the CEO pushes the key decisions about the right balance between investment in new and core businesses down into the units, ceding much of his or her own power and creating a collection of feudal baronies.” (emphasis added)  (p76). 

Amazing! Now innovation doesn’t have a single friend.

Communications are poor and cynicism is pervasive

We learn also that communications are far from open and authentic:
 “when leaders attempt to deliver inspiring messages, many employees react with skepticism, question whether leaders are just trying to work harder.” (p.98)

As a result:
“In many companies the majority of frontline employees are cynical about leaders’ motives and intentions.”

The lack of transparency is a two-way street. Following one presentation to the C-suite, one CEO questioned the presenter:
“When I pressed him, he admitted that he didn’t agree with anything he had just said and that he was presenting what he had been told to present.” (p.79).

False assumptions about motivation

This may be because of wrong assumptions about motivation:
“In national surveys, over the past three decades, the majority of American shave identified meaningful work as the single most important feature they seek in a job.”(p.98)

But:
Rarely do executives suggest imbuing the work with greater meaning and purpose. Fewer than 1% say that managers should show … how [employees'] work makes a difference.” (p.98) (emphasis added).

Most executives start from the assumption that employees are ultimate self-interested, proposing performance incentives such as pay increases, promotions, recognition, food and breaks—interventions that… managers had already tried to no avail.” (p.99). (emphasis added)

The problems are systemic

The problems are not just a few individuals straying from the way. The problems are structural and systemic:

“In many companies, innovation units find themselves measured against the performance standards of the core business. This puts the innovation unit at a disadvantage as it struggles to a well-established business that has proven itself.” (p. 79)

The constraints are embedded in the very systems by which firms are being run.
“One obstacle is the profit center structure which makes it impossible to consider a product’s revenues and costs separately. Another is the cost accounting system which is not good for identifying the actual expense of generating new offerings.” (p.138).

It should not be surprising therefore that given these management practices and attitudes
“some think it’s foolish to even attempt to create innovative-growth businesses.” (p.72)

The disastrous results of these management practices

It should hardly be surprising therefore that the results of these management practices are dismal. As shown by Deloitte’s magisterial study of 20,000 US firms between 1965 to 2010,
  • The rate of return on assets is only one quarter of what it was in 1965.
  • The life expectancy of firms in the Fortune 500 has declined from around 75 years half a century ago to less than 15 years and continuing to decline.
  • Executive turnover is accelerating.
  • The topple rate of leading firms is increasing.
  • Only one in five workers is fully engaged in his or her work.
Nor should we really be surprised at the finding by the Kauffman Foundation that between 1980 and 2005 in the US, firms older than five years created practically no new net jobs. Almost all of the 40 million net new jobs were created by firms younger than five years.

And should we really be surprised to find that the US economy is undergoing a series of jobless recoveries, while most people’s incomes remain flat?

The lowly status of innovation today

The disastrous picture of the typical big firm that emerges from these articles is extraordinary:
  • Instead of innovation being regarded as one the firm’s two main functions, management typically assigns innovation low priority.
  • Both CEOs and mid-level managers exhibit pervasive attitudes and behaviors that are hostile to innovation.
  • Innovation receives inadequate resources and staff.
  • Managers do not communicate authentically to inspire staff to innovate.
  • Processes and accounting systems conspire to undermine innovation.
According to the articles, we are not dealing with a few ineffective managers or a few minor problems amid basically sound management practices.

In effect, the problems of innovation are systemic and structural and common to most large organizations.

Systemic problems require systemic solutions

To deal with systemic and structural problems, effective solutions need to be systemic and structural.

For the most part, however, as we shall see in later parts of this review, the recommendations contained in the various HBR articles are based on one-shot actions by individual CEOs or managers. These single-fix solutions deal with symptoms of the problem, rather than the underlying disease.

The apparent short-terms gains from these one-time individual single-fix solutions are unlikely to survive the relentless antagonistic pressure of embedded managerial attitudes, habits, practices, processes and systems.
In effect, the leash from which “Great Leaders” need to “unleash” their organizations is none other than management itself. For innovation to flourish on a sustained basis, individual one-shot actions are not enough. Management itself must be transformed.


Solving The Innovation Enigma:

Logo for Procter & Gamble. Source of the logo.Image via Wikipedia  
As noted yesterday in part 1 of this article, the June issue of Harvard Business Review puts a spotlight on product innovation with four separate articles
  • “P&G’s Innovation Factory”: How Procter & Gamble [PG] has gone from achieving 15% of the profit and revenue objectives in 2000 to 50% today by setting up an “innovation factory” (p. 64)
  • “The ambidextrous CEO”: How the “ambidextrous CEO” at Misys (and elsewhere) handles the tension between innovation and core products (p.74)
  • Intuit’s catalyzing employees”: How Scott Cook at Intuit [INTU] helped catalyze his employees to innovate by hiring a lot of innovation coaches (p. 82).
  • Gold in the reject pile:” How Rain Bird (among other firms) discovered hidden gold in its reject pile (p.88).
The four ideas are presented separately like pieces of a jigsaw puzzle that has not been put together.

None of the articles attempts to explain why the typical corporation systematically undermines innovation, as discussed in the first part of this article, namely:
  • Instead of innovation being regarded as one the firm’s two main functions, management typically assigns innovation low priority.
  • Both CEOs and mid-level managers exhibit pervasive attitudes and behaviors that are hostile to innovation.
  • Innovation receives inadequate resources and staff.
  • Managers do not communicate authentically to inspire staff to innovate.
  • Processes and accounting systems conspire to undermine innovation.
  • Organizational structures (“profit centers”) and traditional cost accounting get in the way of innovation.
The articles offer no coherent explanation of the innovation enigma, i.e. why do most managers—highly intelligent, well-educated and well-paid—think, speak and act in a way that undermines innovation and thus the future of the organization and ultimately the economy. In the articles, it  is taken for granted that this is what “often” happens in “most organizations.” It’s the way things are. There is no attempt to explain why this is the way things are. Without understanding why things are this way, the proposed solutions risk not dealing with the real problem.

None of the articles for example explains that these beliefs, attitudes and behaviors reflect a mental model of management that was dominant in the 20th Century and is still pervasive in the Fortune 500 today.
The main principles of this mental model can be seen in most management textbooks and many business school teachings. They comprise:
  • The goal of the organization is to produce goods and services through a supply chain that makes money for the shareholders.
  • The role of the manager is a boss, namely, a hierarchical controller of individuals.
  • The coordination of work is achieved through rules, plans and reports, i.e. bureaucracy.
  • The predominant value of the organization is efficiency, principally by saving money and economies of scale.
  • Communications are hierarchical in nature, through commands and instructions.
The principles are interlocking, so that attempts to change any one by itself will be undermined by the other principles.

These interlocking principles also help explain why innovation has such a hard time in organizations today.
They also explain why the separate innovation ideas in the four HBR articles are by themselves unlikely to provide a lasting solution to the enigma of innovation.

The ambidextrous CEO

Thus the “ambidextrous CEO” (p.74)—who, the article says, is often the “only friend” of innovation in the whole organization (p,78)—will be pitted against the perceived goal of the organization to make money and the role of the managers to get the supply chain moving ever more efficiently. Even if the occasional CEO succeeds in encouraging innovation in the short term, eventually the systemic forces of the mental model of traditional management will cause the organization to revert back to its “normal” mode of operation—grinding out the core products and services to make money for shareholders. Since managers are rewarded for making money in their “profit center”, they will be tempted to focus on making money and neglecting innovation. The chances of a single “ambidextrous CEO” consistently winning battles against this array of systemic forces are low.

The “ambidextrous CEO” is thus likely to be become another management casualty. More seriously, the firm itself will become another organizational casualty as it fails to innovate fast enough for today’s marketplace, where continuous innovation is a necessity.

A single ambidextrous individual is not enough to generate continuous innovation on a sustainable basis. What is needed instead is for everybody in the organization to become ambidextrous in managing the tension between core products and innovation. The article, alas, gives no hint that this might be possible or how to accomplish it. With everything resting on the heroic shoulders of a single individual—the “Great Leader”—the system of traditional management will be the inexorable winner. Systems are more powerful than individuals.

 

Catalyzing staff

Similarly the excellent idea of Scott Cook at Intuit to use coaches to catalyze staff to get on with the task of innovation through rapid experiments with customers (p.82) may get short term results, as one can see from the rapid rise in share price of once Intuit succeeded in generating continuous innovation to delight its customers.



Over time, however, unless Intuit changes the fundamental assumptions of traditional management, managers, financial controllers and consultants will question the substantial resources being spent on “innovation coaches” (“What’s the rate of return?”) and prove in detailed spreadsheets that the company would be more profitable if it focused more sharply on making money for the shareholders. If the principles of traditional management remain in place, eventually the firm will succumb to the arguments and declare success and fire the coaches so that it can improve the bottom line with tighter control of employees, more elaborate plans, more frequent reporting, and clearer instructions to become more efficient. In effect, the system of traditional management will eventually defeat the individuals trying to do things differently.

 

P&G’s innovation factory

In the Procter & Gamble article (p.64), we see a more ambitious effort over ten years to graft an “innovation factory” on to the structures and processes of traditional management. Managers of “profit centers” are now assigned new-growth goals. Processes are put in place to achieve the new growth through sustaining innovations, commercial innovations, and sustaining-transformational innovations, as well as disruptive innovations that undermine existing businesses. The processes include training on disruptive innovation, innovation manuals, innovation guides, an innovation college and a FutureWorks division. The impressive results over ten years include a doubling of Tide’s revenues over ten years, new products such as cheap razors for developing countries and even a new-style dry cleaning business.

Whereas in 2000, P&G’s new growth efforts were achieving only 15% of their targets, now they are accomplishing 50% of their targets. The progress is impressive. P&G has doubled its share price over ten years and is doing better than traditional stalwarts like GE, Wal-Mart or Cisco. But this progress leaves open the question: why is P&G only half-way towards meeting its new-growth goals?

The answer is not difficult to detect if one reads the HBR article carefully. The large-scale innovation effort is in tension with the underlying assumptions of traditional management which the article indicates are still largely intact at P&G. The goal of the firm is still perceived to be that of making money for shareholders with each “profit center” responsible for achieving its part of the goal. Innovation is seen as another way of making money. In the “innovation factory”, the managers still act as bosses or controllers of individuals. The work of the “innovation factory” is still coordinated with the familiar bureaucracy of traditional management through “stage gates”, reports and financial targets. In such an environment, it is not surprising that, despite the massive management effort and support, innovation still has a hard time fully thriving.

Solving the innovation enigma: systemic change

What would it take for P&G to achieve 100% of their growth targets? What would it take for firms like Misys and Intuit to achieve innovation on a sustained basis like firms such as Apple, Amazon or Salesforce.com with exponential growth in their respective share prices over many years?
To accomplish these kinds of exponential gains on a sustained basis, single-fix ideas of the kind presented in these HBR articles will not do the job.

Resolving the enigma of innovation entails recognizing that the problem is systemic. To solve it, the solution itself must also be systemic. In effect, the underlying principles of traditional management need to be transformed. Management has to be reinvented.

Reinventing management: five basic shifts

A number of books point to the principles of the transformation of management, including my book, The Leader’s Guide to Radical Management (Jossey-Bass 2010), The New Capitalist Manifesto by Umair Haque, The Power of Pull by John Hagel, John Seely Brown and Lang Davison  Reorganize for Resilience by Professor Ranjay Gulati, The Responsible Business by Carol Sanford, and Leadership in a Wiki World by Rod Collins. There are five major shifts:
“Delighting the customer” is an operational business objective, not some vague, abstract or subjective chimera. Measurement is central.
Individually, none of these shifts is new. What is new is doing them together as systemic change. When only one or two of these shifts is pursued without the others, the change tends to be unsustainable because any improvements are undermined by conflicts with the principles of traditional management.

The tension between innovation & core products dissolves

Once these principles replace the principles of traditional management, it becomes clear why traditional management systematically fails at innovation as well as how the separate and seemingly unconnected ideas of the articles in HBR fit within a coherent set of interlocking management principles. As a result, innovation has the possibility of being sustainable. Innovation is no longer fighting with the firm’s own DNA. Innovation has become part of that DNA.
Specifically:
  • Once the goal of the firm is to delight the customers, the CEO is no longer “the only friend of innovation” (p.75). Now everyone in the entire organization is focused on delighting the customers with a clear line of sight to customers so that everyone knows whether and to what extent customer is being delighted. Innovation becomes part of everyone’s job.
  • Now it is no longer a big deal whether it is the CEO handles “the tension between innovation and core products” or whether this is delegated to middle managers because now everyone in the organization is tasked with resolving the tension in the way that best delights the customer.
  • Now the middle managers are evaluated not just on how much money they are making the shareholders, with the temptation to shortchange innovation to plug holes in the budget for core products (p.78). Now the middle managers are evaluated on whether they are delighting the customers, for which innovation is essential. Merely grinding out the core products won’t get the job done.
  • Because the firm is consistently measuring progress in delighting customers, there is much less temptation for individual managers to divert money from innovation to core products: the impact of any such diversions will be systematically revealed by the firm’s measurement systems.
  • Because delighting the customer is much more profitable in today’s marketplace than grinding out the firm’s core products, there is no longer any tradeoff between innovation and making money. Innovation becomes hugely profitable.
  • Innovation stops being “an irritating drain on resources” or “a threat to managers”, because the goal of delighting the customer makes it part of everyone’s job.
  • Because delighting the customer and continuous innovation are now central parts of everyone’s job, there is little temptation for middle managers to staff innovation activities with part-time assignments, as happens in traditional management (p. 71). When customer delight is the firm’s goal, innovation becomes the most important task, requiring the best people.
  • Because the organization adopts the values of radical transparency and horizontal communications, along with the processes needed to support those values, managers and employees stop saying things they don’t believe (p.79). As a result, impediments to innovation are identified and problems get solved earlier.
  • Because managers communicate transparently and horizontally rather than through top-down commands, the risk of apathy and cynicism is drastically reduced. (p. 98).
  • Because the organization adopts throughput accounting techniques, in addition to rudimentary cost accounting (cf. p. 138), managers can see clearly what how financial resources relate to the goals of innovation and delighting customers.
  • Because the firm sees its mission as delighting customers, rather than making money for shareholders, it looks at its divisions as “customer delight centers” rather than merely as “profit centers”. As a result, the organizational structure doesn’t get in the way of promoting innovation (cf. p. 138).

Coherent management principles for innovation

Once the principles of radical management are adopted, the ideas for innovation mentioned in the HBR articles can be seen for what they are: good single-fix ideas that will only work sustainably if they are adopted as part of a coherent set of management principles that are very different from traditional managment:
  • The ambidextrous CEO who can reconcile the tension between innovation and core products (p. 74) is not a bad idea. It’s just not a big enough idea to resolve the enigma of innovation. For innovation to flourish, everyone in the organization must be ambidextrous. And that will only happen sustainably if the basic management assumptions change.
  • The idea of catalyzing staff at Intuit through coaching to accelerate innovation (p. 82) is a good idea. Self-organizing teams are a central feature of innovation. But by itself, delegating to staff is not enough. For such innovation to flourish sustainably, the goal of the firm, the role of managers, the processes for coordinating work, the values of the firm and the communications also have to change.
  • The idea at P&G of putting in place systems and processes to promote innovation (p.64) is a good idea, but implementation will be hobbled, if the systems and processes are grafted on to the principles of traditional management, which are inherently antagonistic to innovation.
  • The idea of looking through the reject pile to find usable innovation (p.88) is a good idea, but it would be even more powerful if it wasn’t just a one-off initiative, but rather the job of everyone every day. For instance, at Toyota, employees come up with around a million innovation suggestions every year.
  • The idea of using customers to inspire employees (p.96) is an excellent idea, but again, implementation will be hobbled unless the goal of the firm shifts from making money for shareholders to delighting customers, and work is coordinated by dynamic linking so that customer feedback is built into everyone’s job.
Tomorrow, in part 3 of this article, I will talk more on the significance of dynamic linking, and show how it resolves the false dichotomy between chaos and bureaucracy.

 Bureaucracy, anarchy & innovation amnesia:

Thomas Edison, half-length portrait, facing front
Image via Wikipedia: Thomas Edison

P&G’s innovation factory

In the June 2011 HBR article on P&G, (p.64), we learn that after ten years of effort, massive investments of financial and human resources, and the strongest possible top management support, Procter & Gamble [PG] has been able to improve performance from achieving only 15% of its new-growth profit and revenue targets in 2000 to around 50% today. This progress is impressive. But the question remains: why after all this effort is P&G still only half-way towards meeting its new-growth goals?

First disconnect: the factory image

P&G is a large old organization (127,000 employees, founded in 1837). It is perhaps not surprising that its leaders set out to build an innovation “factory”. According to the article, it was designed to be a combination of the creativity of Thomas Edison’s industrial research lab (circa 1870) and the speed and reliability of Henry Ford’s production line (circa 1910).
The thinking and imagery are thus early 20th Century in provenance and industrial in nature. The assumption seems to be that the way to succeed in business is to invent something (Edison) and then deliver it (Ford). The thinking is inside-out: “we make it and customers will take it.” The crucial question whether any customer will actually buy your invention is not explicit.
This thinking and imagery were valid for much of the 20th Century when big oligopolies were in charge of the marketplace. But it is out of sync with the 21st Century marketplace reality where there has been a power shift from seller to buyer: the customer is now the boss. The customer now has good information as to what is available and many options to choose from. Whether the firm can invent and build new products has become less important than whether customers will actually buy them. Unless customers are delighted, they won’t.

In practice, we learn in the article that the customer is very much present in P&G’s innovation activities. Thus in addition to the $2 billion spent on research and development, P&G spends “$400 million in foundational consumer research, conducting some 20,000 studies involving more than 5 million consumers in nearly 100 countries.”

There is also a recognition at P&G that “there needs to be an emotional component as well—a source of inspiration that motivates people. At P&G, that inspiration lies in a sense of purpose driven from the top down—the message that each innovation improves people’s lives.”

But when innovation is managed by “profit centers”, it is clear that the message about improving people’s lives is subordinated to the dominant management message: make money for the shareholders.
When a company does one thing, while telling people to do another, the risk of organizational dysfunction is significant. It can lead to the introduction of processes and systems that don’t fit what the work of innovation requires.

Second disconnect: bureaucracy

In fact, the processes that P&G set up to handle innovation as described in the article sound like bureaucracy. The managers of the profit centers are assigned new-growth goals. To help achieve those goals, processes have been put in place that include formal training, manuals, guides, a “robust stage-gate process”, portfolio management, an innovation college, courses on entrepreneurial thinking and disruptive innovation and a FutureWorks division.

Such arrangements provide a sense or order, comfort and familiarity to managers steeped in a culture of 20th Century manufacturing. The arrangements might be appropriate for activities whose parameters and dynamics are largely known and predictable. It is less obvious that they are good fit for the complex, mercurial, inherently unpredictable world of disruptive innovation in the 21st Century, where new business models and platforms are rapidly transforming apparently mature sectors.

This is not to say that innovation can’t happen in a bureaucracy. The experience of P&G has shown some remarkable individual successes. But the fact that P&G is only attaining 50% of its new growth objectives after ten years of massive effort suggests that there is still room for improvement. Whether bureaucracy is the right way to manage innovation is perhaps one of the avenues that P&G management might want to explore.

Genpact: “light a fire and see what happens”

At the opposite end of the spectrum, in the same issue of HBR, there is an account of a non-bureaucratic startup (p. 45). As head of GE Capital in India, Pramod Bhasin tells how he set out in the late 1990s to offer back-office services across GE Capital. He created a division that was eventually spun off as a separate company, Genpact [G], thus giving birth to an entire outsourcing industry.

Bhasin explains:
“I didn’t do any business plan modeling or studies to prove that an opportunity existed. To me it was obvious. I knew that if we could get sophisticated technology to support us… we had the raw talent to offer our services at a small fraction of the cost elsewhere…

We couldn’t just sit down and do the proper analysis to plan it, because this was uncharted territory. We did draw up a business plan, but there was so much finger-in-the-air stuff that I don’t think it had much credibility. We didn’t even know at the start how big the venture could be. We just said: “Let’s light a fire and see what happens.”

Bhasin was ultimately successful in growing the idea into a separate organization with 45,000 employees and sales of $1.2 billion that was spun off from GE. It operates 39 facilities in 13 countries and serving 400 other companies.

Bhasin’s non-bureaucratic approach of “lighting a fire and seeing what happens” was successful in part because of his energy and entrepreneurial spirit, and in part because the nature of the services to be provided was already known and Bhasin had a large existing customer for the services of his division.

Looking across the broader field of innovation today, where the key issue is whether customers will buy the innovation, the approach of “lighting a fire and seeing what happens” has not been consistently successful, as it tends to lead to anarchy. Big investments end being made for products that no one will buy. Since such experiences are anathema in a large organization, organizations tend to re-introduce the controls of bureaucracy.

Often managers often think that these are the only two alternatives: bureaucracy or anarchy. Since the firm doesn’t want anarchy, it is stuck with bureaucracy.

In reality, a quarter of century ago, we learned in the pages of Harvard Business Review itself that there is a third alternative.

What works in innovation: dynamic linking

In 1986 in a famous article entitled, “The New New Product Development Game,” Professors Hirotaka Takeuchi and Ikujiro Nonaka described how a range of firms had been successful in innovation. Some of the examples were in Japan, like Toyota, Fuji Film, and Honda, and a couple were American firms like HP, 3M, and Xerox. They showed how these companies had set up teams that became extraordinarily innovative and productive—without bureaucracy.

Typically the companies set up self-organizing teams. They analyzed the competitive threat and then pulled together a team of their very best people. It was generally a cross-functional team, with people from R&D, engineering, finance, sales, marketing, and support.

They would then give the team a challenging mission. At Honda, for instance, the challenge was to design a car that would appeal to young people and yet be cheap and of high quality. Then they would step back and let the team figure how to make it happen.

At first, the people on the team would be concerned that this was a new form of layoff. After a while, they would settle down and would socialize with each other. And then they would wake up and realize that unless they got cracking, they would never finish by the deadline. So the team would suddenly grasp the urgency of the situation and start to work together.

Takeuchi and Nonaka noted that when this happened, the well-documented phenomenon of self-transcendence within the group would occur. Self-transcendence is a big word, but it simply means that the individuals started to feel that the goals of the team were more important than their own part in it, their own careers, their own preferred position, their prior attitudes. If they were thinking only about themselves—their own goals and their own interests—the team would get locked into suboptimal patterns of work. Takeuchi and Nonaka noted, “A project takes on a self-organizing character as it is driven to a state of ‘zero information’—where prior knowledge does not apply. Ambiguity and fluctuation abound in this state. Left to stew, the process begins to create its own dynamic order.”
The psychology of this phenomenon was described by Mihaly Csikszentmihalyi in his classic book, Flow. He wrote about those times in our lives when, instead of being buffered by anonymous forces, we “feel in control of our actions, masters of our own fate. On the rare occasions that it happens, we feel a sense of exhilaration, a deep sense of enjoyment that is long cherished and that becomes a landmark in memory for what life should be like. . . . The best moments usually occur when a person’s body or mind is stretched to the limits in a voluntary effort to accomplish something difficult and worthwhile.”

Dynamic linking

Since 1986, the approach sketched by Nonaka and Takeuchi has been developed much further, particularly in software development, in a family of practices known as “Lean”, “Agile”, “Scrum” “Kanban” and “Lean Startups”. See for instance my article: “Scrum is a major management discovery.

These practices, which may be collectively called “dynamic linking”, have in common that (a) the work is done in short cycles; (b) the management sets priorities in terms of the goals of work in the cycle, based on what is known about what might delight the client; (c) decisions about how the work is to be carried out to achieve those goals are largely the responsibility of those doing the work; (d) progress is measured (to the extent possible) by direct customer feedback at the end of each cycle.

In dynamic linking, one meshes the efforts of autonomous teams of knowledge workers who have the agility to innovate and meet the shifting needs of clients while also achieving disciplined execution.
As The Power of Pull points out, one proceeds “by setting things up in short, consecutive waves of effort, iterations that foster deep, trust-based relationships among the participants… Knowledge begins to flow and team begins to learn, innovate and perform better and faster.… Rather than trying to specify the activities in the processes in great detail.., specify what they want to come out of the process, providing more space for individual participants to experiment, improvise and innovate.”

It’s not bureaucracy and it’s not anarchy. It gets the best of all worlds. It has the decisiveness of a hierarchical bureaucracy but without its inflexibility, its rigidity and its tendency to de-motivate workers and frustrate customers. It creates an environment that is radically more productive for the organization, more congenial to innovation, and more satisfying both for those doing the work and those for whom the work is done.
It’s been implemented for over fifteen years in organizations large and small with great success. It’s discussed in detail in chapters 6 and 7 of The Leader’s Guide to Radical Management: Reinventing the Workplace for the 21st Century , along with the specific practices needed to make it operational.

Management amnesia

Intellectual disciplines that advance systematically keep track of the evolution of the subject. Writers are careful to give credit to predecessors, signal alternative viewpoints and demonstrate sensitivity to the evolution of the subject as a whole.

By contrast, in subjects that don’t advance, journals systematically eliminate traces of earlier thinking about the subject at hand. It is as though the articles have “a virgin birth” and emerge into the world without any legitimate parentage.

Thus you could read the articles on product innovation in the June issue of HBR without being made aware of the famous 1986 HBR article, “The New New Product Development Game,” Professors Hirotaka Takeuchi and Ikujiro Nonaka, which paved for the way for the later management discoveries of Agile, Scrum and Kanban, and Lean Startups. There is a lack of historical perspective in the writing.

As a result, P&G ‘s “innovation factory” can be presented as “a big new thing”, when in reality more advanced thinking about innovation was available in HBR itself some twenty-five years ago.

At the same time, some amnesia might be valuable. It could be useful for instance to forget about the romanticized version of the hierarchical bureaucracies of Thomas Edison (circa 1870s) and Henry Ford (circa 1910).

With a suitably clear mind, one could then focus on the world of 2011 and examine how companies like Apple, Amazon and Salesforce.com are getting exponential gains from innovation by radically transforming management.

In effect, the leash from which “Great Leaders” need to “unleash” their organizations is none other than management itself.


See earlier post:

Radical management: it’s happening! make more money!

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Saturday, 11 June 2011

Lawyer to sue Khazanah for denying son scholarship





By NG CHENG YEE,chengyee@thestar.com.my

KUALA LUMPUR: A man wants to sue Khazanah Nasional Bhd, Yayasan Khazanah and its director after his son failed to get a scholarship offered by the foundation and the Cambridge Commonwealth Trust.

Lawyer Chan Chow Wang, 67, said he was planning to retire and personally funding son Xiao Yao’s studies would be a huge financial burden.

He also did not understand why Yayasan Khazanah had rejected the application as Xiao Yao had on Jan 5 received a conditional offer for a place at the University of Cambridge.

Yayasan Khazanah works with the Cambridge Commonwealth Trust to offer the Khazanah Cambridge Scholarship to students who have gained admission to the university through the usual application route.

Xiao Yao is scheduled to do his BA Honours degree in Chemical Engineering via Natural Sciences. The course starts in October.



Chan said that when he appealed to the foundation and asked for an explanation for the rejection, all he got was a letter telling him that the competition for the scholarship programme was very stiff.

He added that he would file a suit against the three parties because of the embarrassment, anguish and depression caused to his son.

“I will also lodge a complaint with the Malaysian Anti-Corruption Commission and request it to investigate the scholarship programme,” he said at a press conference yesterday.

Chan said the tuition fee for his son’s first-year study was £18,000 (about RM89,000) while the college fee was £4,462.50 (about RM22,000).

“With living expenses, my son will need about RM150,000 a year for this four-year degree programme and it is a huge sum of money,” he said.

Chan said it would be difficult for him to fund his son’s education as he was planning to retire in two years.

He had also funded the education of his four children, including Xian Yao’s education up to A-level.
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